hypoxic$37119$ - определение. Что такое hypoxic$37119$
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Что (кто) такое hypoxic$37119$ - определение

HYPOXIC CONDITIONS IN TUMOR CELLS
Hypoxic tumor; Tumour hypoxia
  • Regulatory pathway of PFK-1 by fructose-2,6-bisphosphate
  • GLUT1 Glucose Transporter
  • Overview of the HIF-1 effect on the expression of glycolytic enzymes
  • HIF regulates interactions of cancer cells with ECM and ECM biosynthesis
  • The Structure of Lactic Acid
  • Schematic highlighting the metabolic symbiosis formed between hypoxic and normoxic tumor cells
  • The areas surrounding the phosphorylation sites on pyruvate dehydrogenase are shown in red. Pyruvate dehydrogenase kinase phosphorylation of these sites leads to decreased dehydrogenase activity
  • Tumour stroma and extracellular matrix in hypoxia

Intermittent hypoxic training         
Intermittent Hypoxic Training
Intermittent hypoxic training (IHT), also known as intermittent hypoxic therapy technique aimed at improving human performance by way of adaptation to reduced oxygen.
Hypoxic Training Index         
  • How the HTi is calculated:  Only part of the IHT session is shown, the targeted [[SpO2]] value is 80% as an example. The filled part of the [[SpO2]] graph represents the amount of hypoxia delivered, “dosage”.
IN RESPIRATION THERAPY
Hypoxic training index
The Hypoxic Training index (HTi) provides an objective measure of the hypoxic stress delivered during the Intermittent Hypoxic Training (IHT) session, compared to simple recording the inhaled fraction of oxygen (FiO2). HTi provides a figure (index) of dosage received by the individual at the end of the session.
Hypoxic ventilatory response         
  • [[Cusco]], Peru, which has an altitude of 11,000 ft
  • Simien Mountains 14,900 ft
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BIOLOGICAL REACTION TO INCREASED ALTITUDE
Hypoxic Ventilatory Response (HVR)
Hypoxic ventilatory response (HVR) is the increase in ventilation induced by hypoxia that allows the body to intake and process oxygen at higher rates. It is initially elevated in lowlanders who travel to high altitude, but reduces significantly over time as people acclimatize.

Википедия

Tumor hypoxia

Tumor hypoxia is the situation where tumor cells have been deprived of oxygen. As a tumor grows, it rapidly outgrows its blood supply, leaving portions of the tumor with regions where the oxygen concentration is significantly lower than in healthy tissues. Hypoxic microenvironements in solid tumors are a result of available oxygen being consumed within 70 to 150 μm of tumour vasculature by rapidly proliferating tumor cells thus limiting the amount of oxygen available to diffuse further into the tumor tissue. In order to support continuous growth and proliferation in challenging hypoxic environments, cancer cells are found to alter their metabolism. Furthermore, hypoxia is known to change cell behavior and is associated with extracellular matrix remodeling and increased migratory and metastatic behavior.